Y.H.P. Skin patch testing can be utilized to confirm clinical suspicion for an allergic reaction to Dermabond. Her wounds were closed with Vicryl sutures (Ethicon), deep dermal polydioxanone sutures (Ethicon), key sutures with Prolene (Ethicon), and Dermabond on the skin. Call 911 if you have: Simple home and over-the-counter (OTC) treatments can treat contact dermatitis as well. Although the use of topical skin adhesives has increased as an alternative to conventional skin closure methods, studies on the incidence and risk factors of ACD to topical skin adhesives have been limited. 2017 Dec;77(6):414-415. doi: 10.1111/cod.12823. The authors did not receive support from any organization for the submitted work. To address this issue, we reviewed 1027 patients who underwent skin closure with 2-octyl cyanoacrylate and n-butyl cyanoacrylate topical skin adhesives to investigate the incidence and risk factors of ACD to topical skin adhesives. 2022. Epub 2020 Sep 3. The .gov means its official. Google Scholar. You are using a browser version with limited support for CSS. Diffuse Cutaneous Allergic Reaction to Dermabond, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MassachusettsUSA, Department of Physical Medicine and Rehabilitation, Thomas Jefferson University Hospital, Philadelphia, PennsylvaniaUSA, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MassachusettsUSA, https://doi.org/10.1017/S1049023X14001010, Get access to the full version of this content by using one of the access options below. Generally, very few complications are associated with Dermabond and are usually related to application techniques. 0000002088 00000 n 2021GR145), 1167 patients who underwent skin closure with topical skin adhesives in our institution between April 2017 and February 2021 were investigated for study eligibility. Ardis AE (1949) US patent nos. It can have many causes, from Zika virus to allergies. These materials can irritate the skin or cause an allergic reaction in some people. Technol. Scientific Reports (Sci Rep) J. Adhes. Once applied, this film is left to dry and usually lasts five to 10 days on the skin. Singer AJ, Quinn JV, Hollander JE (2008) The cyanoacrylate topical skin adhesives. Dermabond () surgical glue had been applied to the skin at wound closure; the glue residue remained on the skin for several days. Thus, allergic reactions should only increase as laparoscopic and robotically assisted hysterectomy replace open abdominal and vaginal techniques. Pediatr Emerg Care. The dermatologist made recommendation to apply a thin topical layer of hydrocortisone 1% to affected areas two to four times per day. After that, a standard absorbent dressing was applied and changed on the second day after surgery. In some cases, your doctor may want to perform a skin biopsy as well. Wound closure with 2-octyl cyanoacrylate (Dermabond; Ethicon, Somerville, New Jersey USA) has recently increased in popularity across a wide spectrum of physicians ranging from surgeons to emergency medicine practitioners. Care 20, 219223 (2004). The National Eczema Association says that people who have allergies to any of those things or if the skin is irritated by them may end up with a rash called contact dermatitis. Osmond, M. H., Quinn, J. V., Sutcliffe, T., Jarmuske, M. & Klassen, T. P. A randomized, clinical trial comparing butylcyanoacrylate with octylcyanoacrylate in the management of selected pediatric facial lacerations. Given the case history, the patient was likely sensitized to Dermabond from prolonged exposure to embedded Dermabond from a previous procedure. 0000068029 00000 n 2018 Gorski J. Thus, the increasingly large number of hysterectomies being performed with traditional laparoscopic and robotically-assisted laparoscopic techniques may contribute to a gross underestimation of the actual number accomplished. Does DERMABOND PRINEO System cause any allergic reactions? With the escalation in Dermabond usage, which can be attributed to its speed and convenience, more allergic reactions are anticipated. PMC This report describes a rare case of a diffuse cutaneous allergic reaction to Dermabond following its use to close a surgical incision, its prompt identification, and treatment after presentation to an emergency department. in four of eight patients tested, and to 2-hydroxyethyl methacrylate in one of eight patients tested. Publication types Case Reports MeSH terms Breast Implantation / adverse effects 0000059447 00000 n After approval from the local ethics committee (Korea University Guro Hospital Institutional Review Board, No. Please enable it to take advantage of the complete set of features! Blackmore, Sid Prior to this study, four studies have reported the incidence of ACD in the use of 2-octyl cyanoacrylate topical skin adhesive. Data, Authorship & Author This decline has been attributed to the introduction of minimally invasive techniques such as uterine artery embolization for the treatment of leiomyomata and non-surgical ablative therapies that are now commonly used for abnormal benign uterine bleeding [1]. The exclusion criteria included age<18years, inflammatory disease (e.g., rheumatoid arthritis or psoriatic arthritis), active infection in the area of incision prior to surgery, or follow-up of less than 6weeks. Disclaimer. 0000017254 00000 n Embedded Dermabond may result in a foreign body reaction.8 This report describes contact dermatitis from the use of Dermabond. 120, 14601465 (2007). Nunley, Julia The clinical characteristics of patients with allergic contact dermatitis (ACD) due to a skin adhesive containing 2-octyl cyanoacrylate, Dermabond, have not yet been elucidated. None of the patients received systemic steroid therapy or wound revision. Dermabond was first approved by the US Food and Drug Administration in 1998 and has steadily increased in popularity. Michalowitz, A., Comrie, R., Nicholas, C., Wagner, M. & Kehoe, J. Medication for eczema and dermatitis. A 36-year-old white woman on postoperative day four. Radiol. eCollection 2021. Cite this article. In the meantime, to ensure continued support, we are displaying the site without styles and Drug-related problems in hypertension and gestational diabetes mellitus: A hospital cohort. 2014; 29 (5): 1-3. Type IV hypersensitivity reactions following Dermabond adhesive utilization in knee surgery: A Report of Three Cases.

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